Testing for antineutrophil cytoplasmic antibodies (ANCAs) in patients with systemic vasculitides and other diseases

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Testing for antineutrophil cytoplasmic antibodies (ANCAs) in patients with systemic vasculitides and other diseases.

To the editor, In the excellent study recently published in the Annals of the Rheumatic Disease, Damoiseaux et al showed a high diagnostic performance of antigen-specific immunoassay for the detection of myeloperoxidase (MPO) and proteinase 3 (PR3) antineutrophil cytoplasmic antibodies (ANCAs). These data challenge the role of indirect immunofluorescence in the ANCA testing algorithm. In our ce...

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Antineutrophil Cytoplasmic Antibodies in Patients with Pulmonary Tuberculosis

Background: Mycobacterium tuberculosis is a major cause of mortality and morbidity worldwide. Infection with this bacterium is known to induce the development of autoantibodies of which a few are also known to be diagnostic markers for some other diseases. Antineutrophil Cytoplasmic Antibodies (ANCA's) are among those autoantibodies used in clinical setting for diagnosing systemic vasculitic sy...

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The antineutrophil cytoplasmic antibody-associated vasculitides.

Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome are small- to medium-vessel vasculitides linked by overlapping pathology and the presence of antineutrophil cytoplasmic antibodies (ANCA). Commonly referred to as the ANCA-associated vasculitides, these diseases are challenging to diagnose and to treat. Distinguishing the ANCA-associated vasculitides from other forms...

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antineutrophil cytoplasmic antibodies in patients with pulmonary tuberculosis

background: mycobacterium tuberculosis is a major cause of mortality and morbidity worldwide. infection with this bacterium is known to induce the development of autoantibodies of which a few are also known to be diagnostic markers for some other diseases. antineutrophil cytoplasmic antibodies (anca's) are among those autoantibodies used in clinical setting for diagnosing systemic vasculit...

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Antineutrophil cytoplasmic antibodies in rheumatoid arthritis patients.

We determined the occurrence of antineutrophil cytoplasmic antibodies (ANCAs) and their specificities in 77 rheumatoid arthritis (RA) patients and compared them with 25 patients with psoriatic arthritis (Pso), 19 with drug-induced lupus erythematosus (DI-LE) and 11 with systemic lupus erythematosus (SLE). Thirty-two percent of RA patients had positive indirect immunofluorescence (IIF) stains (P...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2016

ISSN: 0003-4967,1468-2060

DOI: 10.1136/annrheumdis-2016-210890